Polyelectrolyte-modified short microchannel for cation separation

被引：23

作者：

Bai, XX ^{[1
]}

Roussel, C ^{[1
]}

Jensen, H ^{[1
]}

Girault, HH ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Chim Mol & Biol, Lab Electrochim Phys & Analyt, CH-1015 Lausanne, Switzerland

来源：

ELECTROPHORESIS | 2004年 / 25卷 / 06期

关键词：

capillary electrophoresis; cation separation; microchannel; miniaturization; polyelectrolyte; surface modification;

D O I：

10.1002/elps.200305771

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Three alkali cations, potassium, sodium, and lithium, have been separated within 15 s in a 1 cm long polymer microchip. The separation microchannel is modified by a polycation, poly(allylammonium chloride), which makes the channel surfaces positively charged leading to a reversed electroosmotic flow (EOF) when compared to bare channels. Due to the decreased apparent mobility of the cations, the separation resolution is improved allowing the use of shorter channels.

引用

页码：931 / 935

页数：5

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