A method of improving the spatial resolution of treatments that involve a multileaf collimator

被引:17
作者
Evans, PM
Partridge, M
机构
[1] Inst Canc Res, Joint Phys Dept, Sutton SM2 5PT, Surrey, England
[2] Royal Marsden NHS Trust, Sutton SM2 5PT, Surrey, England
关键词
D O I
10.1088/0031-9155/45/3/304
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In this paper we present a novel method of reducing the dosimetric effects of the finite leaf width of a multileaf collimator (MLC) in conformal and intensity modulated radiotherapy (IMRT). This is achieved by decomposing the required high-resolution fluence distribution into two orthogonal components, which are delivered with two leaf sweeps with head-twists differing by 90 degrees. Before the decomposition stage, a filter is applied to the required beam to force it to have a constant gradient in the two delivery directions. The component deliveries were found to be very spiky in nature, resulting in very inefficient delivery with the scanning leaves of our MLC. This method was evaluated using him dosimetry of four idealized beams: a 45 degrees edge, a circle, a hemispherical intensity modulated beam (IMB) and a sine-like IMB. The measurements showed that this method had significantly reduced the effects of the 1 cm leaf width or our MLC at the 50% isodose level, but there was significant overdosage at the edge of the field and immediately inside the field edge. This method shows promise but further work is required before it may find clinical utility.
引用
收藏
页码:609 / 622
页数:14
相关论文
共 22 条
[1]  
BOYER A L, 1991, Medical Physics (Woodbury), V18, P606
[2]   Rectangular edge synchronization for intensity modulated radiation therapy with dynamic multileaf collimation [J].
Budgell, GJ ;
Sykes, JR ;
Wilkinson, JM .
PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (10) :2769-2784
[3]   Generation of discrete beam-intensity modulation by dynamic multileaf collimation under minimum leaf separation constraints [J].
Convery, DJ ;
Webb, S .
PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (09) :2521-2538
[4]   THE GENERATION OF INTENSITY-MODULATED FIELDS FOR CONFORMAL RADIOTHERAPY BY DYNAMIC COLLIMATION [J].
CONVERY, DJ ;
ROSENBLOOM, ME .
PHYSICS IN MEDICINE AND BIOLOGY, 1992, 37 (06) :1359-1374
[5]   Commissioning of a micro multi-leaf collimator and planning system for stereotactic radiosurgery [J].
Cosgrove, VP ;
Jahn, U ;
Pfaender, M ;
Bauer, S ;
Budach, V ;
Wurm, RE .
RADIOTHERAPY AND ONCOLOGY, 1999, 50 (03) :325-336
[6]   THE ACCEPTABILITY OF A MULTILEAF COLLIMATOR AS A REPLACEMENT FOR CONVENTIONAL BLOCKS [J].
FERNANDEZ, EM ;
SHENTALL, GS ;
MAYLES, WPM ;
DEARNALEY, DP .
RADIOTHERAPY AND ONCOLOGY, 1995, 36 (01) :65-74
[7]   Field edge smoothing for multileaf collimators [J].
Galvin, JM ;
Leavitt, DD ;
Smith, AA .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1996, 35 (01) :89-94
[8]   CHARACTERIZATION OF A MULTILEAF COLLIMATOR SYSTEM [J].
GALVIN, JM ;
SMITH, AR ;
LALLY, B .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 25 (02) :181-192
[9]   Use of a multileaf collimator as a dynamic missing-tissue compensator [J].
Geis, P ;
Boyer, AL ;
Wells, NH .
MEDICAL PHYSICS, 1996, 23 (07) :1199-1205
[10]   THE DESIGN AND PERFORMANCE-CHARACTERISTICS OF A MULTILEAF COLLIMATOR [J].
JORDAN, TJ ;
WILLIAMS, PC .
PHYSICS IN MEDICINE AND BIOLOGY, 1994, 39 (02) :231-251