Efficient nickel-mediated intramolecular amination of aryl chlorides

被引：173

作者：

Omar-Amrani, R ^{[1
]}

Thomas, A ^{[1
]}

Brenner, E ^{[1
]}

Schneider, R ^{[1
]}

Fort, Y ^{[1
]}

机构：

[1] Univ Nancy 1, UMR CNRS UHP 7565, F-54506 Vandoeuvre Les Nancy, France

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 13期

关键词：

D O I：

10.1021/ol034659w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The use of an in situ generated Ni(0) catalyst associated with 2,2'-bipyridine or N,N'-bis(2,6-diisopropylphenyl)dihydroimidazol-2-ylidene (SIPr) as a ligand and NaO-t-Bu as the base for the intramolecular coupling of aryl chlorides with amines is described. The procedure has been applied to the formation of five-, six-, and seven-membered rings.

引用

页码：2311 / 2314

页数：4

共 43 条

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