NIR dyes for bioimaging applications

被引：660

作者：

Escobedo, Jorge O. ^{[1
]}

Rusin, Oleksandr ^{[1
]}

Lim, Soojin ^{[1
]}

Strongin, Robert M. ^{[1
]}

机构：

[1] Portland State Univ, Dept Chem, Portland, OR 97207 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2010年 / 14卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SQUARAINE-DERIVED ROTAXANES; TUNABLE FLUORESCENT DYES; NEAR-INFRARED DYES; BACTERIAL-INFECTION; CYANINE DYES; IN-VITRO; PROBES; FLUOROPHORES; BRIGHT;

D O I：

10.1016/j.cbpa.2009.10.022

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fluorescent dyes based on small organic molecules that function in the near infrared (NIR) region are of great current interest in chemical biology. They allow for imaging with minimal autofluorescence from biological samples, reduced light scattering, and high tissue penetration. Herein, examples of ongoing NIR fluorophore design strategies as well as their properties and anticipated applications relevant to the bioimaging are presented.

引用

页码：64 / 70

页数：7

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