Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

被引：42

作者：

Ropartz, Loic

Meeuwenoord, Nico J.

van der Marel, Gijsbert A.

van Leeuwen, Piet W. N. M.

Slawin, Alexandra M. Z.

Kamer, Paul C. J. ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

[2] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WV Amsterdam, Netherlands

[3] Leiden Univ, Gorlaeus Labs, Leiden Inst Chem, NL-2333 CC Leiden, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 15期

关键词：

D O I：

10.1039/b617871e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

引用

页码：1556 / 1558

页数：3

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