Modular synthesis of ChiraClick ligands: A library of P-chirogenic phosphines

被引：52

作者：

Dolhem, Franck

Johansson, Magnus J.

Antonsson, Thomas

Kann, Nina ^{[1
]}

机构：

[1] Chalmers Univ Technol, Dept Chem & Biol Engn, SE-41296 Gothenburg, Sweden

[2] AstraZeneca R&D, SE-43183 Molndal, Sweden

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2007年 / 9卷 / 03期

关键词：

D O I：

10.1021/cc0601635

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A library of novel and diverse P-chirogenic phosphine ligands containing a triazole moiety (ChiraClick ligands) were prepared in high yield in a modular fashion that allows for variation of both the phosphine and the triazole structure, as well as giving access to the two enantiomers of the ligand.

引用

页码：477 / 486

页数：10

共 53 条

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