Cobalt(II)-Catalyzed cross-coupling between polyfunctional arylcopper reagents and aryl fluorides or tosylates

被引：110

作者：

Korn, TJ ^{[1
]}

Schade, MA ^{[1
]}

Wirth, S ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 04期

关键词：

D O I：

10.1021/ol0529142

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Organocopper compounds prepared by the transmetalation of functionalized arylmagnesium halides with CuCN-2LiCl undergo smooth cross-coupling reactions with aryl fluorides and tosylates bearing a carbonyl function in the ortho position in the presence of Co(acac)(2) (7.5 mol%), Bu(4)Nl (1 equiv), and 4-fluorostyrene (20 mol %) as promoters in DME/THF/DMPU leading to polyfunctional aromatics or heterocycles.

引用

页码：725 / 728

页数：4

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