Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C-H/C-O Bond Arylations with Phenols in Water

被引：133

作者：

Ackermann, Lutz ^{[1
]}

Pospech, Jola ^{[1
]}

Potukuchi, Harish Kumar ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 08期

关键词：

CARBON-CARBON BONDS; BIARYL CONSTRUCTION; ACTIVATION; PALLADIUM; FUNCTIONALIZATION; ETHERS; CLEAVAGE; ARENES; ALKENYLATIONS; ELECTROPHILES;

D O I：

10.1021/ol300671y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ruthenium(II) carboxylate complex [Ru(O(2)CMes)(2)(p-cymene)] enabled efficient direct arylations of unactivated C-H bonds with easily available, inexpensive phenols. Extraordinary chemoselectivity of the well-defined ruthenium catalyst set the stage for challenging C-H/C-O bond functionalizations to occur under solvent-free conditions as well as in water, and allowed first direct C-H bond arylations with user-friendly diaryl sulfates as electrophiles.

引用

页码：2146 / 2149

页数：4

共 82 条

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