Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles

被引：171

作者：

Ackermann, Lutz ^{[1
]}

Wang, Lianhui ^{[1
]}

Lygin, Alexander V. ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

CHEMICAL SCIENCE | 2012年 / 3卷 / 01期

关键词：

C BOND FORMATION; INDOLE SYNTHESES; DIRECT ARYLATION; H ACTIVATION; FUNCTIONALIZATION; ALKALOIDS; CLEAVAGE; LAMELLARINS; ALKENE; AIR;

D O I：

10.1039/c1sc00619c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ruthenium-catalyzed aerobic oxidative annulations of alkynes were accomplished with co-catalytic amounts of Cu(OAc)(2)center dot H2O under ambient air. The C-H/N-H bond functionalization occurred with unparalleled selectivities and ample scope to deliver structural analogs of bioactive marine alkaloids.

引用

页码：177 / 180

页数：4

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